Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.1.1.242

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.1.1.242

Enzymes and Genes:
16S rRNA m2G1516 methyltransferase Inferred from experiment : rsmJ ( Escherichia coli K-12 substr. MG1655 )

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 16S rRNA (guanine1516-N2)-methyltransferase

Enzyme Commission Synonyms: yhiQ (gene name), rsmJ (gene name), m2G1516 methyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -34.742218 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme specifically methylates guanine1516 at N2 in 16S rRNA.

Citations: [Basturea12]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.1.1.242 , ENZYME:EC:2.1.1.242 , IUBMB-ExplorEnz:EC:2.1.1.242

Credits:
Created in EcoCyc 22-Nov-2011 by Keseler I , SRI International
Imported from EcoCyc 05-Dec-2011 by Caspi R , SRI International
Revised 06-Dec-2011 by Caspi R , SRI International


References

Basturea12: Basturea GN, Dague DR, Deutscher MP, Rudd KE (2012). "YhiQ is RsmJ, the methyltransferase responsible for methylation of G1516 in 16S rRNA of E. coli." J Mol Biol 415(1);16-21. PMID: 22079366

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, BIOCYC14A.