|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 126.96.36.199
Enzymes and Genes:
|Escherichia coli K-12 substr. MG1655 :||16S rRNA m2G1516 methyltransferase
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 16S rRNA (guanine1516-N2)-methyltransferase
Enzyme Commission Synonyms: yhiQ (gene name), rsmJ (gene name), m2G1516 methyltransferase
Taxonomic Range: Bacteria
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -34.742218 [Latendresse13]
Enzyme Commission Summary:
The enzyme specifically methylates guanine1516 at N2 in 16S rRNA.
Basturea12: Basturea GN, Dague DR, Deutscher MP, Rudd KE (2012). "YhiQ is RsmJ, the methyltransferase responsible for methylation of G1516 in 16S rRNA of E. coli." J Mol Biol 415(1);16-21. PMID: 22079366
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