|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Composite Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: all-trans-phytoene synthase
Enzyme Commission Synonyms: prephytoene-diphosphate synthase (ambiguous), phytoene synthetase (ambiguous), PSase (ambiguous), geranylgeranyl-diphosphate geranylgeranyltransferase (ambiguous), 15-trans-phytoene synthase
Standard Gibbs Free Energy (ΔrG'°): -21.45996 kcal/mol [Latendresse13]
Enzyme Commission Summary:
Requires Mn2+ for activity. The enzyme from the bacterium Pantoea agglomerans (previously known as Erwinia herbicola) produces the all-trans isomer of phytoene. cf. EC 126.96.36.199, 15-cis-phytoene synthase.
Gregonis74: Gregonis DE, Rilling HC (1974). "The stereochemistry of trans-phytoene synthesis. Some observations on lycopersene as a carotene precursor and a mechanism for the synthesis of cis- and trans-phytoene." Biochemistry 13(7);1538-42. PMID: 4819767
IwataReuyl03a: Iwata-Reuyl D, Math SK, Desai SB, Poulter CD (2003). "Bacterial phytoene synthase: molecular cloning, expression, and characterization of Erwinia herbicola phytoene synthase." Biochemistry 42(11);3359-65. PMID: 12641468
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