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MetaCyc Reaction: 1.3.1.M4

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical ReactionsProtein-Modification Reactions
Reactions Classified By SubstrateMacromolecule ReactionsProtein-ReactionsProtein-Modification Reactions

EC Number: 1.3.1.M4

Enzymes and Genes:

Mycobacterium tuberculosis H37Rv: meromycolic acid enoyl-[acyl-carrier-protein] reductaseInferred from experiment: inhA

In Pathway: mycolate biosynthesis

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: meromycolic acid enoyl-[acyl-carrier-protein] reductase

Enzyme Commission Synonyms: inhA (gene name)

Standard Gibbs Free Energy (ΔrG): 34.414047 kcal/molInferred by computational analysis [Latendresse13]

Citations: [Quemard95]

Gene-Reaction Schematic

Gene-Reaction Schematic


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Quemard95: Quemard A, Sacchettini JC, Dessen A, Vilcheze C, Bittman R, Jacobs WR, Blanchard JS (1995). "Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis." Biochemistry 34(26);8235-41. PMID: 7599116


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 20.0 (software by SRI International) on Fri May 6, 2016, BIOCYC14.