|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Protein-Modification Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Protein-Reactions → Protein-Modification Reactions|
EC Number: 1.3.1.M4
Enzymes and Genes:
|Mycobacterium tuberculosis H37Rv:||meromycolic acid enoyl-[acyl-carrier-protein] reductase: inhA|
In Pathway: mycolate biosynthesis
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: meromycolic acid enoyl-[acyl-carrier-protein] reductase
Enzyme Commission Synonyms: inhA (gene name)
Standard Gibbs Free Energy (ΔrG'°): 34.414047 kcal/mol [Latendresse13]
Quemard95: Quemard A, Sacchettini JC, Dessen A, Vilcheze C, Bittman R, Jacobs WR, Blanchard JS (1995). "Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis." Biochemistry 34(26);8235-41. PMID: 7599116
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