MetaCyc Reaction: 1.1.1.M9

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical ReactionsProtein-Modification Reactions
Reactions Classified By SubstrateMacromolecule ReactionsProtein-ReactionsProtein-Modification Reactions

EC Number: 1.1.1.M9

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655: 3-oxoacyl-[acyl-carrier-protein] reductase: fabG
Mycobacterium tuberculosis H37Rv: meromycolic acid 3-oxoacyl-[acyl-carrier-protein] reductase: fabG1

In Pathway: mycolate biosynthesis

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Direct generic reaction:
a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ ← a 3-oxoacyl-[acp] + NADPH + H+ (

Enzyme Commission Primary Name: meromycolic acid 3-oxoacyl-[acyl-carrier-protein] reductase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 20.375793Inferred by computational analysis [Latendresse13]

Gene-Reaction Schematic

Gene-Reaction Schematic

Instance reaction of [a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ ← a 3-oxoacyl-[acp] + NADPH + H+] (
i1: a cis-delta5-3-hydroxyC24:1-[acp] + NADP+ ← a cis-delta5-3-oxo-C24:1-[acp] + NADPH + H+ (1.1.1.M9)


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Sun Nov 29, 2015, BIOCYC13A.