|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Antirrhinum majus :||benzaldehyde dehydrogenase
|Corynebacterium glutamicum ATCC 13032 :||acetaldehyde dehydrogenase
|Homo sapiens :|
|Paracoccus denitrificans PD1222 :||aldehyde dehydrogenase (NAD+)
|Pseudomonas oleovorans :||aldehyde dehydrogenase
|Saccharomyces cerevisiae :|
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: aldehyde dehydrogenase (NAD+)
Enzyme Commission Synonyms: CoA-independent aldehyde dehydrogenase, m-methylbenzaldehyde dehydrogenase, NAD-aldehyde dehydrogenase, NAD-dependent 4-hydroxynonenal dehydrogenase, NAD-dependent aldehyde dehydrogenase, NAD-linked aldehyde dehydrogenase, propionaldehyde dehydrogenase, aldehyde dehydrogenase (NAD)
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -15.27533 [Latendresse13]
Enzyme Commission Summary:
Wide specificity, including oxidation of D-glucuronolactone to D-glucarate.
Instance reaction of [an aldehyde + NAD+ + H2O → a carboxylate + NADH + 2 H+] (22.214.171.124):
i1: acetaldehyde + NAD+ + H2O → acetate + NADH + 2 H+ (126.96.36.199)
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