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MetaCyc Reaction: 2.7.1.71

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.1.71

Enzymes and Genes:
shikimate kinase II Inferred from experiment : aroL ( Escherichia coli K-12 substr. MG1655 )
shikimate kinase Inferred from experiment : aroK ( Methanocaldococcus jannaschii )
shikimate kinase Inferred from experiment : SK2 ( Arabidopsis thaliana col )
shikimate kinase Inferred from experiment : SK1 ( Arabidopsis thaliana col )
pentafunctional AROM polypeptide Inferred from experiment : ARO1 ( Saccharomyces cerevisiae )
shikimate kinase Inferred from experiment : aroI ( Bacillus subtilis )

In Pathway: chorismate biosynthesis from 3-dehydroquinate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: shikimate kinase

Enzyme Commission Synonyms: shikimate kinase (phosphorylating), shikimate kinase II

Standard Gibbs Free Energy (ΔrG in kcal/mol): -16.064087 Inferred by computational analysis [Latendresse13]

Citations: [Morell68]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R02412 , Rhea:13121

Relationship Links: BRENDA:EC:2.7.1.71 , ENZYME:EC:2.7.1.71 , IUBMB-ExplorEnz:EC:2.7.1.71 , UniProt:RELATED-TO:P07547 , UniProt:RELATED-TO:P08566 , UniProt:RELATED-TO:P0A6D7 , UniProt:RELATED-TO:P0A6E1 , UniProt:RELATED-TO:P10880 , UniProt:RELATED-TO:P34003 , UniProt:RELATED-TO:P37944 , UniProt:RELATED-TO:P43880 , UniProt:RELATED-TO:P43906 , UniProt:RELATED-TO:P63600 , UniProt:RELATED-TO:P72796 , UniProt:RELATED-TO:Q9CEU1 , UniProt:RELATED-TO:Q9PIB5 , UniProt:RELATED-TO:Q00497


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Morell68: Morell H, Sprinson DB (1968). "Shikimate kinase isoenzymes in Salmonella typhimurium." J Biol Chem 243(3);676-7. PMID: 4866525


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sat Mar 28, 2015, BIOCYC13A.