MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655: trehalose-6-phosphate phosphataseInferred from experiment: otsB
Mycobacterium smegmatis: trehalose-6-phosphate phosphataseInferred from experiment: otsB
Phormia regina: trehalose phosphataseInferred from experiment
Saccharomyces cerevisiae: trehalose-6-phosphate phosphataseInferred from experiment
trehalose-6-phosphate phosphataseInferred from experiment: TPS2
trehalose synthase complexInferred from experiment: TPS3, TSL1, TPS2, TPS1

In Pathway: trehalose biosynthesis II, trehalose biosynthesis III, trehalose biosynthesis I

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: trehalose-phosphatase

Enzyme Commission Synonyms: trehalose 6-phosphatase, trehalose 6-phosphate phosphatase, trehalose-6-phosphate phosphohydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 7.217041Inferred by computational analysis [Latendresse13]

Citations: [Cabib58, Candy61]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R02778, KEGG:R06228, Rhea:23420

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:O64896, UniProt:RELATED-TO:O64897, UniProt:RELATED-TO:P31678, UniProt:RELATED-TO:P31688, UniProt:RELATED-TO:P78875, UniProt:RELATED-TO:Q00786


Cabib58: Cabib E, Leloir LF (1958). "The biosynthesis of trehalose phosphate." J Biol Chem 231(1);259-75. PMID: 13538966

Candy61: Candy DJ, Kilby BA (1961). "The biosynthesis of trehalose in the locust fat body." Biochem J 78;531-6. PMID: 13690400

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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