|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Polynucleotide-Reactions → RNA-Reactions → tRNA-Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Escherichia coli K-12 substr. MG1655 :||tRNA C32 thiolase
ThiI : thiI
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balance undetermined; a substrate lacks a chemical formula
Enzyme Commission Primary Name: tRNA sulfurtransferase
Enzyme Commission Synonyms: transfer ribonucleate sulfurtransferase, RNA sulfurtransferase, ribonucleate sulfurtransferase, transfer RNA sulfurtransferase, transfer RNA thiolase
Enzyme Commission Summary:
A group of enzymes transferring sulfur to various nucleotides in a tRNA chain, producing residues such as 4-thiouridylate. With some enzymes mercaptopyruvate can act as sulfur donor.
Abrell71: Abrell JW, Kaufman EE, Lipsett MN (1971). "The biosynthesis of 4-thiouridylate. Separation and purification of two enzymes in the transfer ribonucleic acid-sulfurtransferase system." J Biol Chem 246(2);294-301. PMID: 5541999
Wong70: Wong TW, Weiss SB, Eliceiri GL, Bryant J (1970). "Ribonucleic acid sulfurtransferase from Bacillus subtilis W168. Sulfuration with beta-mercaptopyruvate and properties of the enzyme system." Biochemistry 9(11);2376-86. PMID: 4987417
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