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MetaCyc Reaction: 3.5.1.5

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.5.1.5

Enzymes and Genes:

Glycine max : urease Inferred from experiment : EU4
urease Inferred by computational analysis : EU1
Sinorhizobium meliloti Rm2011 : urease Inferred from experiment : ureC , ureB , ureA
Streptococcus salivarius : urease Inferred from experiment : ureC , ureB , ureA

In Pathway: urea degradation II

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: urease

Standard Gibbs Free Energy (ΔrG in kcal/mol): -5.9629974 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
A nickel protein.

Citations: [Dixon76]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R00131

Relationship Links: BRENDA:EC:3.5.1.5 , ENZYME:EC:3.5.1.5 , IUBMB-ExplorEnz:EC:3.5.1.5 , UniProt:RELATED-TO:O00084 , UniProt:RELATED-TO:O86508 , UniProt:RELATED-TO:P07374 , UniProt:RELATED-TO:P08298 , UniProt:RELATED-TO:P14916 , UniProt:RELATED-TO:P16122 , UniProt:RELATED-TO:P16123 , UniProt:RELATED-TO:P16124 , UniProt:RELATED-TO:P17086 , UniProt:RELATED-TO:P17087 , UniProt:RELATED-TO:P17088 , UniProt:RELATED-TO:P17272 , UniProt:RELATED-TO:P17273 , UniProt:RELATED-TO:P17274 , UniProt:RELATED-TO:P17337 , UniProt:RELATED-TO:P17338 , UniProt:RELATED-TO:P17339 , UniProt:RELATED-TO:P18316 , UniProt:RELATED-TO:P31494 , UniProt:RELATED-TO:P31496 , UniProt:RELATED-TO:P41020 , UniProt:RELATED-TO:P41021 , UniProt:RELATED-TO:P41022 , UniProt:RELATED-TO:P42873 , UniProt:RELATED-TO:P42874 , UniProt:RELATED-TO:P42875 , UniProt:RELATED-TO:P42885 , UniProt:RELATED-TO:P42886 , UniProt:RELATED-TO:P42887 , UniProt:RELATED-TO:P44391 , UniProt:RELATED-TO:P44392 , UniProt:RELATED-TO:P44393 , UniProt:RELATED-TO:P69996 , UniProt:RELATED-TO:P69997 , UniProt:RELATED-TO:P73061 , UniProt:RELATED-TO:P73796 , UniProt:RELATED-TO:Q9R2X6 , UniProt:RELATED-TO:Q9R5F4 , UniProt:RELATED-TO:Q9R5F5 , UniProt:RELATED-TO:Q9R5F6 , UniProt:RELATED-TO:Q9R5F8 , UniProt:RELATED-TO:Q9R5X1 , UniProt:RELATED-TO:Q9RFF2 , UniProt:RELATED-TO:Q9RFF4 , UniProt:RELATED-TO:Q9RFF5 , UniProt:RELATED-TO:Q03282 , UniProt:RELATED-TO:Q07397 , UniProt:RELATED-TO:Q07398 , UniProt:RELATED-TO:Q07399 , UniProt:RELATED-TO:Q08715 , UniProt:RELATED-TO:Q08716 , UniProt:RELATED-TO:Q41214


References

Dixon76: Dixon NE, Gazzola C, Blakeley RL, Zerner B (1976). "Metal ions in enzymes using ammonia or amides." Science 191(4232);1144-50. PMID: 769157

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Apr 26, 2015, biocyc14.