|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
Enzymes and Genes:
cytosolic 5'-nucleotidase II : NT5C2 ( Homo sapiens )
5'-nucleotidase : NT5E ( Homo sapiens )
UMP phosphatase : umpH ( Escherichia coli K-12 substr. MG1655 )
pyrimidine nucleotidase : yjjG ( Escherichia coli K-12 substr. MG1655 )
broad specificity 5'(3')-nucleotidase and polyphosphatase : umpG ( Escherichia coli K-12 substr. MG1655 )
5'-ribonucleotidase : ushA ( Escherichia coli K-12 substr. MG1655 )
acid phosphatase / phosphotransferase : aphA ( Escherichia coli K-12 substr. MG1655 )
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 5′-nucleotidase
Enzyme Commission Synonyms: uridine 5'-nucleotidase, 5'-adenylic phosphatase, adenosine 5'-phosphatase, AMP phosphatase, adenosine monophosphatase, 5'-mononucleotidase, AMPase, UMPase, snake venom 5'-nucleotidase, thimidine monophosphate nucleotidase, 5'-AMPase, 5'-AMP nucleotidase, AMP phosphohydrolase, IMP 5'-nucleotidase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 7.217041 [Latendresse13]
Enzyme Commission Summary:
Wide specificity for 5-nucleotides.
Instance reaction of [a ribonucleoside 5'-monophosphate + H2O → a ribonucleoside + phosphate] (126.96.36.199):
i1: XMP + H2O → xanthosine + phosphate (188.8.131.52)
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