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MetaCyc Reaction: 1.8.2.4

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.8.2.4

Enzymes and Genes:

Rhodovulum sulfidophilum : dimethylsulfide dehydrogenase Inferred from experiment : ddhA , ddhB , ddhC

In Pathway: dimethyl sulfide degradation III (oxidation)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: dimethyl sulfide:cytochrome c2 reductase

Enzyme Commission Synonyms: Ddh (gene name)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -6.439476 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme from the bacterium Rhodovulum sulfidophilum binds molybdopterin guanine dinucleotide, heme b and [4Fe-4S] clusters.

Citations: [Hanlon96, McDevitt02]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:1.8.2.4 , ENZYME:EC:1.8.2.4 , IUBMB-ExplorEnz:EC:1.8.2.4

Credits:
Revised 04-Mar-2011 by Caspi R , SRI International


References

Hanlon96: Hanlon SP, Toh TH, Solomon PS, Holt RA, McEwan AG (1996). "Dimethylsulfide:acceptor oxidoreductase from Rhodobacter sulfidophilus. The purified enzyme contains b-type haem and a pterin molybdenum cofactor." Eur J Biochem 239(2);391-6. PMID: 8706745

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

McDevitt02: McDevitt CA, Hugenholtz P, Hanson GR, McEwan AG (2002). "Molecular analysis of dimethyl sulphide dehydrogenase from Rhodovulum sulfidophilum: its place in the dimethyl sulphoxide reductase family of microbial molybdopterin-containing enzymes." Mol Microbiol 44(6);1575-87. PMID: 12067345


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Fri Jul 3, 2015, biocyc13.