Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015 (Sat)
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015 (Sat)
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015 (Sat)
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015 (Sat)
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015 (Sat)
twitter

MetaCyc Reaction: 1.8.2.4

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.8.2.4

Enzymes and Genes:

Rhodovulum sulfidophilum : dimethylsulfide dehydrogenase Inferred from experiment : ddhA , ddhB , ddhC

In Pathway: dimethyl sulfide degradation III (oxidation)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: dimethyl sulfide:cytochrome c2 reductase

Enzyme Commission Synonyms: Ddh (gene name)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -6.439476 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme from the bacterium Rhodovulum sulfidophilum binds molybdopterin guanine dinucleotide, heme b and [4Fe-4S] clusters.

Citations: [Hanlon96, McDevitt02]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:1.8.2.4 , ENZYME:EC:1.8.2.4 , IUBMB-ExplorEnz:EC:1.8.2.4

Credits:
Revised 04-Mar-2011 by Caspi R , SRI International


References

Hanlon96: Hanlon SP, Toh TH, Solomon PS, Holt RA, McEwan AG (1996). "Dimethylsulfide:acceptor oxidoreductase from Rhodobacter sulfidophilus. The purified enzyme contains b-type haem and a pterin molybdenum cofactor." Eur J Biochem 239(2);391-6. PMID: 8706745

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

McDevitt02: McDevitt CA, Hugenholtz P, Hanson GR, McEwan AG (2002). "Molecular analysis of dimethyl sulphide dehydrogenase from Rhodovulum sulfidophilum: its place in the dimethyl sulphoxide reductase family of microbial molybdopterin-containing enzymes." Mol Microbiol 44(6);1575-87. PMID: 12067345


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Wed Sep 2, 2015, biocyc13.